Graham & McNeney Labs

Research

Software developed

Recent Publications

2023
2022
2021
2020
2019
2018
2017
2016
2014
2013
2012
2011
2010
2008

NB: In 2008-09, McNeney was on sabbatical leave and Graham was on parental leave.

2007
2006
2004 and 2005

Posters

June 2024 2024 Meeting of the European Society for Human Genetics, Online poster session; ATXN2 gene variants in neurodegenerative diseases. D Jethnani (presenter), J Lubieniecka, K Lubieniecki, S Bernsen, K Audoire, M Yusenko, C Hippert, K Doring, N Jovancevic, S Hofjan, P Weydt, J Graham, H Nguyen
Sept. 2022 International Genetic Epidemiology Society Annual Meeting, Paris; An Exploration of Linkage Fine-Mapping on Sequences from Case-Control Studies. P Nickchi, C Karunarathna and J Graham (presenter)
Sept. 2022 International Genetic Epidemiology Society Annual Meeting, Paris; Inference of gene-environment interaction from heterogeneous case-parent trios}. P Ratnasekera, J Graham and B McNeney (presenter)
May 2022 Annual Meeting of the Statistical Society of Canada, online; Sampling Partial Genealogies Using Sequential Importance Sampling. D Liu (presenter) and J Graham
Oct. 2021 International Genetic Epidemiology Society Annual Meeting, online; A Comparison of Association Methods for Fine-mapping Rare Variants in Case-Control Studies. P Nickchi (presenter) C Karunarathna and J Graham
Oct. 2021 International Genetic Epidemiology Society Annual Meeting, online; Shrinkage Parameter Estimation in Penalized Logistic Regression Analysis of Case-Control Data. Y Yu (presenter) S Chen and B McNeney
Oct. 2021 International Genetic Epidemiology Society Annual Meeting, online; Re-analysis of a Genome-Wide Gene-By-Environment Interaction Study of Case Parent Trios, Adjusted for Population Stratification. P Ratnasekera (presenter), J Graham and B McNeney
May 2019

Annual Meeting of the Statistical Society of Canada, Calgary AB; Sampling Partial Genealogies Using Sequential Importance Sampling. D Liu (presenter) and J Graham.
August 2018 Workshop on New Statistical Methods for Family-Based Sequencing Studies, Banff International Research Station (BIRS), Banff, AB; SimRVSequences: Simulating Sequence Data for Pedigrees. C Nieuwoudt (presenter), A Brooks-Wilson and J Graham.
August 2018 Workshop on New Statistical Methods for Family-Based Sequencing Studies, Banff International Research Station (BIRS), Banff, AB; On Using Gene Genealogies to Find Trait-Influencing Variants, P Nickchi (presenter) and J Graham.
August 2018 Workshop on New Statistical Methods for Family-Based Sequencing Studies, Banff International Research Station (BIRS), Banff, AB; Sampling Partial Genealogies Using Sequential Importance Sampling. Dongmeng Liu (presenter) and Jinko Graham.
July 2018 2018 Joint Statistical Meeting (JSM), Vancouver, BC; On Using Gene Genealogies to Find Trait-Influencing Variants, P Nickchi (presenter) and J Graham
June 2018 7th Annual Canadian Human and Statistical Genetics Meeting,  Harrison Hot Springs Resort, BC; On Using Gene Genealogies to Find Trait-Influencing Variants, P Nickchi (presenter) and J Graham.
June 2018 7th Annual Canadian Human and Statistical Genetics Meeting, Harrison Hot Springs, BC; SimRVSequences: Simulating Sequence Data for Pedigrees. C Nieuwoudt (presenter), A Brooks-Wilson, and J Graham.
July 2016 28th International Biometrics Conference, Victoria, BC; Using Gene Genealogies to Understand the Patterns of Case-control Association in Sequencing Data. CB Karunarathna (presenter) and J Graham.
April 2015 Fourth Annual Canadian Human and Statistical Genetics Meeting, Vancouver, BC; Using Gene Genealogies to Understand the Patterns of Case-control Association. CB Karunarathna (presenter) and J Graham.
April 2015 Fourth Annual Canadian Human and Statistical Genetics Meeting, Vancouver, BC; Is There Anticipation in the Age of Onset of Familial Lymphoid Cancers? D Liu (presenter), S Jones, R Thomas, GW Slack, JM Connors, A Brooks-Wilson, and J Graham.
April 2015 Fourth Annual Canadian Human and Statistical Genetics Meeting, Vancouver, BC; Principal Component-based Analysis of High-dimensional Gene Expression Guided by Clinical Data. JM Lubieniecka (presenter), J Graham, A Sarmiento, KL Brown, C Ross, R Luqmani, D Foell, E Gill, REW Hancock, S Benseler, DA Cabral.
April 2015 Fourth Annual Canadian Human and Statistical Genetics Meeting, Vancouver, BC; Prioritizing Rare Variants in Lymphoid Cancer Families. C Nieuwoudt (presenter), J Graham, S Jones, R Thomas, GW Slack, JM Connors, and A Brooks-Wilson.
April 2015 Fourth Annual Canadian Human and Statistical Genetics Meeting, Vancouver, BC; Joint Analysis of Imaging and Genomic Data to Identify Associations Related to Cognitive Impairment. E Szefer (presenter) MF Beg and J Graham.
May 2014 Third Annual Canadian Human and Statistical Genetics Meeting, Victoria, BC; Controlling for Ethnicity Using Supervised Principal Components in Genetic Association Studies. E Szefer (presenter) and J Graham.
May 2014 Third Annual Canadian Human and Statistical Genetics Meeting, Victoria, BC; Genetics of Pediatric ANCA-associated Vasculitides (AAVs). JM Lubieniecka (presenter), J Graham, A Sarmiento, KL Brown, C Ross, R Luqmani, D Foell, REW Hancock, S Benseler and DA Cabral
October 2013 Workshop on Coalescent Theory: New Developments and Applications, Montreal, QC.  Coalescent Model Through Simulations. B Jonoska Stojkova and WL Premarathna (co-presenters).
October 2012 International Genetic Epidemiology Meeting, Steveston WA.  Incorporating gene genealogies in rare variant mapping methodology. K Burkett (presenter), B McNeney, J Graham and C Greenwood.
October 2012 International Genetic Epidemiology Meeting, Steveston WA.  A data-smoothing approach to graphical displays and testing of  gene-environment interaction using data from case-parent trios. J-H Shin (presenter), C Infante-Rivard, B McNeney and J Graham
April 2012 Inaugural  Canadian Human & Statistical Genetics Meeting, Niagara-on-the-Lake, ON.   Sampling genealogies conditional on unphased genotype data.  K Burkett (presenter), B McNeney and J Graham.
April 2012 Inaugural  Canadian Human & Statistical Genetics Meeting, Niagara-on-the-Lake, ON.   A data-smoothing approach to graphical displays and testing of  gene-environment interaction using data from case-parent trios. J-H Shin (presenter), C Infante-Rivard, B McNeney and J Graham.
May 2011 6th Annual Canadian Genetic Epidemiology & Statistical Genetics Meeting, King City, ON.   Sampling genealogies conditional on genotype data at surrounding markers. K Burkett (presenter) , B  McNeney and J Graham.
May 2011 6th Annual Canadian Genetic Epidemiology & Statistical Genetics Meeting, King City, ON.   Testing gene-environment interaction in case-parent trios when we do not have a causal SNP.  J-H Shin (presenter), C Infante-Rivard, J Graham and B  McNeney
April 2011 CRM Workshop in Computational Statistical Methods for Genomics and Systems Biology, Montreal QC.  Sampling genealogies conditional on genotype data at surrounding markers. K Burkett (presenter), B. McNeney and J Graham
April 2011 CRM Workshop in Computational Statistical Methods for Genomics and Systems Biology, Montreal QC.  Testing gene-environment interaction in case-parent trios when we do not have a causal SNP.  J-H Shin (presenter), C  Infante-Rivard, J Graham and B. McNeney
August 2010 Joint Statistical Meetings, Vancouver BC.  Graphical displays to uncover gene-environment interaction from data on case-parent trios. J-H Shin (presenter), C. Infante-Rivard, B. McNeney and J Graham.
August 2010 Joint Statistical Meetings, Vancouver BC.  Sampling ancestries at a genomic location conditional on data from surrounding genetic markers. K. Burkett (presenter), B  McNeney and J Graham.
April 2010 5th Annual Canadian Genetic Epidemiology & Statistical Genetics Meeting, King City, ON.  Graphical displays to uncover gene-environment interaction from data on case-parent trios. J-H Shin (presenter), C Infante-Rivard, B McNeney and J Graham
April 2010 5th Annual Canadian Genetic Epidemiology & Statistical Genetics Meeting, King City, ON.  Sampling ancestries at a genomic location conditional on data from surrounding genetic markers. K Burkett (presenter) , B  McNeney and J Graham
April 2010 5th Annual Canadian Genetic Epidemiology and Statistical Genetics Meeting, King City, ON.  Multiple Hypothesis Testing Procedures with Application to Epidemiologic Studies of Genetic. C Qu (presenter), J Spinelli and J Graham
October 2009 Annual Meeting of the International Genetic Epidemiology Society, Kahuku HI.  Sampling ancestries at a genomic location conditional on data from surrounding genetic markers. K Burkett (presenter) , B McNeney and J Graham
June 2009 Annual Meeting of the Statistical Society of Canada, UBC.  Multiple hypothesis testing procedures with applications to epidemiologic studies of genetic susceptibility. C Qu (presenter), J Spinelli and J Graham
June 2009 Annual Meeting of the Statistical Society of Canada, UBC.  A statistical method for high-throughput screening of predicted orthologs.J-E Min (presenter), M Whiteside, F Brinkman, B McNeney and J Graham.
June 2009 Annual Meeting of the Statistical Society of Canada, UBC.  Sampling ancestries at a genomic location conditional on data from surrounding genetic markers. K Burkett (presenter), B McNeney and J Graham
May 2009 4th Annual Canadian Genetic Epidemiology & Statistical Genetics Meeting, Harrison Hot Springs Resort.  Can gene-by-environment interaction be inferred from parent-case transmission rates?J-H Shin (presenter), B McNeney and J Graham.
May 2009 4th Annual Canadian Genetic Epidemiology & Statistical Genetics Meeting, Harrison Hot Springs Resort.  Multiple hypothesis testing procedures with applications to epidemiologic studies of genetic susceptibility. C Qu (presenter) , J Spinelli and J Graham.
May 2009 4th Annual Canadian Genetic Epidemiology & Statistical Genetics Meeting, Harrison Hot Springs Resort.  Sampling ancestries at a genomic location conditional on data from surrounding genetic markers. K Burkett (presenter), B McNeney and J Graham.
September 2008 Annual Meeting of the International Genetic Epidemiology Society, St Louis.  Can Gene-by-Environment Interaction be Inferred from Parent-Case Transmission Rates?J-H Shin (presenter), B McNeney and J Graham.
September 2008 Annual Meeting of the International Genetic Epidemiology Society, St Louis.  Sampling ancestries at a genomic location conditional on data from surrounding genetic markers. K Burkett (presenter),  B McNeney and J Graham.
May 2008 Annual Meeting of the Statistical Society of Canada, Ottawa. Case Study Competition.  Do TNF-alpha gene polymorphisms modify the association between polyunsaturated fatty acids and HDL/apo A-1?  K. Burkett (leader), C. Qu (presenter) , J.-H. Shin (contributor), B McNeney (mentor), J Graham (mentor).
April 2008 Third Annual Canadian Genetic Epidemiology and Statistical Genetics Meeting, Toronto.  Sampling ancestries at a hidden disease locus conditional on data from surrounding genetic. K. Burkett (presenter), B McNeney and J Graham.
September 2007 Annual Meeting of the International Genetic Epidemiology Society, York, England.  Sampling ancestries at a hidden disease locus conditional on data from surrounding genetic markers. K Burkett (presenter),  B McNeney and J Graham.
September 2007 Annual Meeting of the International Genetic Epidemiology Society, York, England.  Inferring Gene-by-Environment Interaction: Do Transmission Rates Reflect Genotype Relative Risks of Disease?J-H Shin (presenter), B McNeney and J Graham.
April 2007 Second Annual Canadian Genetic Epidemiology and StatisticalMeeting, Toronto.  Semiparametric likelihood inference ofassociations with a genetic factor and independent continuousin a case-control study of a rare disease.J-H Shin (presenter), B McNeney and J Graham.
April 2007 Second Annual Canadian Genetic Epidemiology and Statistical Genetics Workshop, Toronto.  Markov Chain Monte Carlo exact inference in logistic regression models.D Zamar (presenter) , B McNeney and J Graham.
November 2005 The Third Seattle Symposium in Biostatistics:Genetics and Genomics.  hapassoc: Software for likelihood inference of trait associations with SNP haplotypes and other attributes. K Burkett (presenter), B McNeney and J Graham.
November 2005 The Third Seattle Symposium in Biostatistics: Statistical Genetics and Genomics.  Semiparametric likelihood inference in case-control studies of a rare disease under independence of genetic and continuous non-genetic covariates, with application to a case-control study of type 1 diabetes. J-H Shin (presenter),  L Bekris, A Lernmark,  B McNeney and J Graham.
October 2005 Annual Meeting of the International Genetic Epidemiology Society, Park City.  Semiparametric maximum likelihood inference of disease associations with a genetic risk factor and independent continuous attribute in a case-control study of type 1 diabetes. J-H Shin (presenter), L Bekris, A Lernmark, B McNeney and J Graham.
May 2005 MITACS Annual Conference and Interchange, Calgary.  A semiparametric likelihood method with improved precision to detecti genetic interactions in type 1 diabetes, J-H Shin (presenter),  L Bekris, A Lernmark, B McNeney and J Graham.
September 2004 Annual Meeting of the International Genetic Epidemiology Society, Noordwijkerhout NL. Semi-parametric likelihood inference of disease associations with a genetic factor and independent continuous attribute in a case-control study. J-H Shin (presenter), L Bekris, T Farin, T Kavanagh, A Lernmark, B McNeney and J Graham.
September 2004 International Genetic Analysis Workshop 14,, Noordwijkerhout NL.  A comparison of three methods selecting tagging SNPs. M Pratola (presenter), M Ghadessi, K Burkett,  J Graham, B McNeney and D Daley.
March 2004 Annual Meeting of the Society of Toxicology, Baltimore.  Glutathione-s-transferase polymorphisms and associations with T1DM. L Bekris (presenter), C Shepard, F Farin, J Graham, B McNeney, T Kavanagh, A Lernmark. 
November 2003
 Annual Meeting of the International Genetic Epidemiology Society, Redondo Beach California. Maximum-likelihood estimation of type 1 diabetes associations with a genetic factor and independent continuous attribute. J-H Shin (presenter), L Bekris, F Farin, T Kavanagh, A Lernmark, B McNeney and J Graham.
November 2003 Annual Meeting of the American Society of Human Genetics, Los Angeles, CA. Incorporating uncertain phase into estimation and testing of haplotype associations. K Burkett (presenter), B McNeney and J Graham
May 2003 MITACS Annual Conference and Interchange, Ottawa.  Incorporating haplotype uncertainty in disease risk estimation. K. Burkett (presenter), B McNeney and J Graham.
October 2002 Annual Meeting of the American Society of Human Genetics, Baltimore, MD. PEDMST, a new program for identity coefficients calculation and IBD patterns enumeration. C Zhu (presenter) and J Graham
August 2002 Eric K. Fernstrom Foundation Symposium on Diabetes, Ystad, Sweden.  Study of multilocus age-dependent genetic effects on type 1 diabetes risk (MAGENTA). J Graham (presenter), B McNeney,  W Hagopian, I Kockum, L Chen, C Sanjeevi, R Lowe, J Schaefer, M Zarghami, H Day, M Landin-Olsson, J Palmer, M Janer-Villanueva, L Hood, G Sundkvist, A Lernmark, N Breslow, G Dahlquist for the Swedish Childhood Diabetes Study Group and G Blohme for the Diabetes Incidence in Sweden Study Group.
October 1997 Annual Meeting of the American Society of Human Genetics, Baltimore, MD. Disequilibrium mapping via coalescent models of gene ancestry. J Graham (presenter) and EA Thompson.